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Microneedling with PRP: What to Expect

Last updated: October 12, 2026 · Reviewed against current source guidance listed below

Preparation

Typical preparation includes a small blood draw to prepare the PRP, performed just before the microneedling session; avoiding certain medications beforehand, such as blood thinners, is often advised by the provider.

Procedure and recovery

The PRP is applied to the skin during or after the microneedling pass. Redness and mild swelling for a day or two is common; results, where evidence supports them, tend to develop gradually over a series of sessions.

Risks to weigh

As with microneedling alone, risks include infection, scarring, and pigment changes; evidence for PRP's added benefit over microneedling alone is still limited and comes mostly from small studies.

Key takeaways
  • Preparation usually includes a blood draw just before the session.
  • Mild redness/swelling afterward is common; results build gradually over sessions.
  • Evidence for PRP's added benefit over microneedling alone is still limited.
When to see a doctor
  • Signs of infection (increasing redness, warmth, pus, fever) after a session.
This article is for general educational purposes only and is not medical advice. It does not replace diagnosis, treatment, or personalized recommendations from a licensed healthcare professional. Hands On Health is an independent blog and is not affiliated with any clinic.